JuniperPublishers-Academic Journal of Pediatrics Neonatology

Juniper Publishers - Journal of Pediatrics Abstract It is a postinfectious polyneuropathy due to alteration of protein component of myelin (p2 neurotogenic peptide) leading to demyelination because of autoimmune mechanism. Neurological manifestation begins after 2 to 4 weeks of viral or bacterial infection. Clinical expression includes an acute onset symmetrical ascending weakness (both proximal & distal) with unilateral facial weakness and respiratory weakness and autonomic dysfunction. The diagnosis depends on clinical picture, electrophysiological findings and CSF examination. Immunotherapy is the main stay of treatment. IVIG & Plasmaphrersis done within 2 to 4 weeks of symptoms onset is recommended. Treatment is warranted in non ambulatory patient (Modified Hughes GBS disability scale). The patient who hav not responded to initial IVIG treatment may benefit from second course of IVIG. General supportive care includes cardiorespiratory care, physiotherap

Juniper Publishers - Journal of Pediatrics Abstract Traumatic pancreatitis is still a relative enigma, despite modern clinical practice, technology and modern diagnostic procedures. This condition is very specific and serious and is associated with significant morbidity, especially in pediatric population. Traumatic pancreatitis is also an emerging problem in pediatric population with its incidence rising in the last 20 years. Data regarding the optimal management and physician practice patterns are lacking. We present a literature review and updates on the management of pediatric pancreatitis due to trauma. Prospective multicenter studies are necessary to guide care and improve outcomes for this population. Keywords: Trauma; Pancreas; Children; Diagnosis; Management Introduction Traumatic pancreatitis is still a relative enigma, despite modern clinical practice, technology and modern diagnostic

Juniper Publishers - Journal of Pediatrics Abstract Congenital hypothyroidism (CH) is the commonest cause of preventable developmental delay with an incidence of 1/3500-4500 newborns. The incidence of symptomatic cases has decreased dramatically in the developed countries with the advent of newborn screening. However, much work still needs to be done in the developing world in improving awareness and devising newborn screening strategies etc. In this article, we discuss the diagnosis and management of congenital hypothyroidism. Keywords: Red blood cell transfusion; Malondialdehyde; Ferritin; Preterm Abbreviations: CH: Congenital Hypothyroidism; DHG: Dyshormonogenesis; TSH: Thyroid Stimulating Hormone; T4: Thyroxine; TBG: Thyroid Binding Globulin; TS: Thyroid Scintigraphy; TRB-Ab: Thyroid Receptor Blocking Antibody; Introduction Congenital hypothyroidism (CH) is the commonest cause of preventable developmental delay with an i

Juniper Publishers - Journal of Pediatrics Abstract Aim: Preterm infants commonly receive at least one packed red blood cell transfusion during their stay in the neonatal intensive care unit and even though the complications related to prematurity are multifactorial, especially bronchopulmonary dysplasia, necrotizing enterocolitis and intraventricular hemorrhage have been shown to be independently related with red blood cell transfusions. This study aims to determine the extent of lipid peroxidation in preterm babies after multiple transfusions, and to figure out acut-off value of ferritin to start or withhold iron prophylaxis in transfused babies. Methods: Serum malondialdehyde and ferritin levels of 23 preterm babies (born earlier than 35th gestational week) were measured and the relation between total number of red blood cell transfusions, malondialdehyde and ferritin levels were assessed. Results: The relations between the transfusion numbers and ferriti

Juniper Publishers - Journal of Pediatrics Abstract Neonatal septicemia is a clinical syndrome of systemic illness accompanied by bacteremia occurring in the first 28 days of life. Micro-organism causing neonatal septicemia varies from country to country and region to region and time to time. In many situations, conventional antibiotics are not sensitive to causative micro-organism. Our aim of the study is to identify causative organism and sensitivity pattern of micro-organism in Neonatal Intensive Care Unit, (NICU) Methods & Subject: Total 300 patients were enrolled in this study with clinically diagnosed septicemia with prior antibiotic treatment or not. This study was done in NICU of tertiary Hospital, Chittagong Medical College, Bangladesh during the period of January 2013 to July 2014. Blood culture was done in Bact/Alerd 3D system. Result: Out of 300 cases, 204 cases were culture negative and 96 cases (32%) were culture positive. Klebsiella is the

Juniper Publishers - Journal of Pediatrics Introduction End-stage renal disease (ESRD) is associated with numerous complications, which may partly result from excessive amounts of reactive oxygen species and/or decreased antioxidant activity [1]. In children in haemodialysis have been described hipozincemia. Given the diverse array of biologic functions of zinc, it is not surprising that multiple physiological and metabolic functions, such as physical growth, immunocompetence, reproductive function, and neurobehavioral development are all affected by zinc status [2]. When the supply of dietary zinc is insufficient to support these functions, biochemical abnormalities and clinical signs may be developed [3]. Objectives Inside of a study of evaluation of the effect of administration of zinc sulphate on nutritional status in children with chronic renal failure, we described a girl’s nutritional status.