JuniperPublishers-Academic Journal of Pediatrics Neonatology

Juniper Publishers - Journal of Pediatrics Abstract Metoclopramide is antiemetic, antinauseant and gastric prokynetic. European medicines agency (EMA) in July 2013 has officially recommended a very restricted use of metoclopramide in children, because of serious and common neurological side effects. A 3 years old boy was admitted to our pediatric department due to altered consciousness, nausea, vomiting and dehydration. Day before he recived a one oral and one intravenous dose of Reglan (metoclopramide). Immidiately after admission he developed dramatic neurological symtoms with face and extremity muscles spasms, trismus, ophistotonus and extreme agitation. Neurological symptoms were present for about 3 hours, with periodically withdrawal and worsening. He received only symptomatic therapy and after 6 hours child was fully recovered and without complaints. Despite repeated warnings about the possible neurological side effects, metoclopramide continues to be used in...

Juniper Publishers - Journal of Pediatrics Abstract Background: Bronchiolitis is a common cause of respiratory failure in children. Respiratory failure, in the PICU, is often managed with the utilization of arterial cannulas and frequent arterial blood gas sampling. Despite the common use of arterial blood sampling, it is unclear if these tests improve outcomes. Objective: To evaluate the frequency of blood draws for blood gas sampling and the duration of mechanical ventilation in children with respiratory failure with bronchiolitis in whom arterial cannel as were placed after initiation of mechanical ventilation.Setting: Children were recruited from a tertiary care children’s hospital. Design: Retrospective cohort study. Setting: TPICU at a tertiary care children’s hospital. Patients: 109 children between 0 to 2 years with a diagnosis of bronchiolitis requiring mechanical ventilation. Methods: A retrospective chart review was conducted on patients ages 0 to...